Liver Cancer Summit 2023


20-22 April, Estoril
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Liver Cancer Summit 2023


20-22 April, Estoril
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P08-4-YI The role of Aurora kinase A in hepatocel.. Luca Grisetti .. Anna Alessia Saponaro, Caecili.. Basic Science.. - -
P09-4-YI Dissecting the tumor heterogeneity and t.. Mareike Polenkowski .. .. Basic Science.. - -
P11-4-YI Time-trends in cholangiocarcinoma incide.. Morten Daniel Jensen .. .. Clinical Science.. - -
P11-5-YI Therapeutic potential of targeting prote.. Paula Olaizola .. .. Basic Science.. - -
P08-5 A novel hepatocellular cancer patient de.. Fabian Haak .. Gabriel Hess, Philipp Sedlacze.. Basic Science.. - -
P10-5 Targeting epigenetics in preclinical mod.. Anastasia Georgakopoulou .. A. GEORGAKOPOULOU1,2, M. MÜLLE.. Basic Science.. - -
P09-5-YI Prognostic impact of metastatic site in .. Luca Ielasi .. .. Clinical Science.. - -
P01-5-YI Predicting cardiovascular risk in patien.. Bernardo Stefanini .. .. Clinical Science.. - -
P03-5 Centrosome amplification is attributed t.. Caroline Oi Ling Yu .. Zhou, YUAN; Wing Lam, CHAN; Y.. Basic Science.. - -
P07-5 The earliest integration of hepatitis B .. Thomas I. Michalak .. Chauhan R, Mulrooney-Cousins P.. Basic Science.. - -
P05-5 ASSOCIATION OF TP53 WITH DEFECTIVE LONG .. Tripti Khare .. .. Basic Science.. - -
P06-5-YI Impact of the covid-19 pandemic on the t.. Laynara Vitória Da Silva Vieira .. .. Clinical Science.. - -
P05-6-YI Preferential effects of PARP-1 inhibitio.. Darko Castven .. .. Basic Science.. - -
P06-6 Gamma-aminobutyric acid B2 receptor as a.. Charupong Saengboonmee .. Supannika Sorin, Sakkarn Sangk.. Basic Science.. - -
P07-6-YI KDM2A histone demethylase ablation resto.. Elisa Morganti .. .. Basic Science.. - -
P04-6-YI Scavenger receptor MARCO is associated w.. Aloña Agirre Lizaso .. .. Basic Science.. - -
P02-6-YI Novel platinum-based chemotherapeutic ag.. Irene Olaizola .. .. Basic Science.. - -
P03-6 Proteomic profile matching predicts trea.. Frederic Saltel .. C. TOULOUSE1,2, M. MOREAU1, M... Basic Science.. - -
P01-6-YI Survival outcomes from Atezolizumab plus.. Margherita Rimini .. Margherita Rimini, Mara Persan.. Clinical Science.. - -
P10-6-YI Metabolic rewiring by increased mitochon.. Naroa Goikoetxea .. .. Basic Science.. - -

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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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