EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER

International Liver Congress™ 2022

 

22-26 June, 2022 London
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THU-48 The most recent and in-depth meta-analyt.. Zobair Younossi .. .. Metabolism, alcohol and toxicity.. - -
FRI-48 The combination of the ELF and FIB-4 sco.. Zobair Younossi .. .. Metabolism, alcohol and toxicity.. - -
THU-49 Comorbidities and Malignancy among NAFLD.. Naim Abu-Freha .. .. Metabolism, alcohol and toxicity.. - -
SAT-49 Chemical suppression of adipose triglyce.. Emmanuel Dauda Dixon .. .. Metabolism, alcohol and toxicity.. - -
FRI-49 Association of the biological age and th.. Anastasiia Radchenko .. .. Metabolism, alcohol and toxicity.. - -
FRI-50 LEARN algorithm: a novel option for pred.. Gang Li .. .. Metabolism, alcohol and toxicity.. - -
THU-50 The prevalence of non-alcoholic fatty li.. Yusef Alenezi .. .. Metabolism, alcohol and toxicity.. - -
SAT-50 Methionine adenosyltransferase 1a antise.. Xabier Buque .. .. Metabolism, alcohol and toxicity.. - -
FRI-51 Head to head comparison between MEFIB ve.. Rohit Loomba .. .. Metabolism, alcohol and toxicity.. - -
SAT-51 NLRP3 inflammasome dependent cell death .. Benedikt Kaufmann .. .. Metabolism, alcohol and toxicity.. - -
THU-51 Health-related quality of life is impair.. Maurice Michel .. .. Metabolism, alcohol and toxicity.. - -
THU-52 Moderate alcohol consumption is associat.. Julia Blomdahl .. Patrik Nasr, Mattias Ekstedt, .. Metabolism, alcohol and toxicity.. - -
SAT-52 The PNPLA3 I148M variant increases intra.. Panu Luukkonen .. .. Metabolism, alcohol and toxicity.. - -
FRI-52 MRI assessment (cT1) with LiverMultiScan.. Naim Alkhouri .. .. Metabolism, alcohol and toxicity.. - -
SAT-53 Two diseases, one model - assessing the .. Sebastian Bott .. .. Metabolism, alcohol and toxicity.. - -
FRI-53 The PNPLA3 (rs738409) G/G-genotype is as.. Hannes Hagstrm .. .. Metabolism, alcohol and toxicity.. - -
THU-53 Prevalence trends of non-alcoholic fatty.. Jaejun Lee .. .. Metabolism, alcohol and toxicity.. - -
FRI-54 Hepatic expression of secreted calcium-b.. Frederik Larsen .. .. Metabolism, alcohol and toxicity.. - -
THU-54 Hepatocellular and extrahepatic cancers .. James Thomas .. .. Metabolism, alcohol and toxicity.. - -
SAT-55 The ubiquitin-like modifier FAT10 is upr.. Ludivine Clavreul .. .. Metabolism, alcohol and toxicity.. - -
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Abstract

Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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