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 THU-41 |
Refining the natural history of alcohol .. | Richard Parker .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-41 |
Phospholipid fingerprints reveal sex dif.. | Gerard Baiges .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-42 |
Quantification of hepatic steatosis in p.. | Rémi Collin .. | Benjamin Buchard, Benoit Magni.. | Metabolism, alcohol and toxicity.. | - - |
| SAT-42 |
Ubiquitination of GSDMD regulated by NED.. | Rui Jin .. | Xiaoxiao Wang, Feng Liu, Huiyi.. | Metabolism, alcohol and toxicity.. | - - |
| THU-42 |
Potential biomarkers for differentiating.. | Adelina Horhat .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-43 |
Unraveling the transcriptional dynamics .. | Geurt Stokman .. | Anita M. van den Hoek, Serdar .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-43 |
Community NAFLD screening programme in p.. | Emma McCormick .. | N Cullen1, E Lillis2, O OHagan.. | Metabolism, alcohol and toxicity.. | - - |
| SAT-44 |
Repeated weight cycling in obese mice im.. | Geurt Stokman .. | Jelle C.B.C. de Jong, Nanda Ke.. | Metabolism, alcohol and toxicity.. | - - |
| THU-44 |
Trends of alcohol-related liver disease .. | Richard Goodheart .. | Koya Ayonrinde.. | Metabolism, alcohol and toxicity.. | - - |
| FRI-44 |
Non-alcoholic fatty liver disease in pat.. | Rasmus Hvidbjerg Gantzel .. | Abdullah Ghassan Muhammad, Fre.. | Metabolism, alcohol and toxicity.. | - - |
| THU-45 |
Increased hospital admissions for alcoho.. | Alexandra Frolkis .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-45 |
A baseline signature of metabolites invo.. | Rohit Loomba .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-45 |
The functional roles of BMP10 in the pat.. | Wenjun Zhang .. | .. | Metabolism, alcohol and toxicity.. | - - |
| THU-46 |
The lysosomal enzyme cathepsin D as a ne.. | Ronit Shiri-Sverdlov .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-46 |
Enchanced Liver Fibrosis test in predict.. | Kustaa Saarinen .. | Kustaa Saarinen1, Martti Frkki.. | Metabolism, alcohol and toxicity.. | - - |
| SAT-46 |
Pharmacokinetics, safety, and tolerabili.. | Giridhar Tirucherai .. | Eric J. Lawitz, Claudia De Ol.. | Metabolism, alcohol and toxicity.. | - - |
| SAT-47 |
Amino acid glycine suppresses steatohepa.. | Kazuyoshi Kon .. | .. | Metabolism, alcohol and toxicity.. | - - |
| THU-47 |
Ductular bilirubinostasis is a diagnosti.. | Annelotte Broekhoven .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-47 |
Radiowater perfusion PET of the liver, a.. | Olof Eriksson .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-48 |
Advanced quantitative phenotypic fibrosi.. | Li Chen .. | .. | Metabolism, alcohol and toxicity.. | - - |
Abstract
Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy
Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.
Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.
Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.
Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.
