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 THU-69 |
Lean non-alcoholic fatty liver disease p.. | Zobair Younossi .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-69 |
PRO-C3 based sequential algorithm can sc.. | Liang-Jie Tang .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-70 |
Real-world use of the FIB-4 calculator i.. | George Therapondos .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-70 |
The role of immune semaphorins in NAFLD .. | Ivana Knezevic Stromar .. | Maja Mijic, Lara Samadan, Slav.. | Metabolism, alcohol and toxicity.. | - - |
| THU-70 |
Automated FIB-4 calculator and targeted .. | Cindy Piao .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-71 |
In silico identification and validation .. | Noel Salvoza .. | Pablo J. Giraudi, Deborah Bona.. | Metabolism, alcohol and toxicity.. | - - |
| THU-71 |
Long term outcomes of non-alcoholic fatt.. | Zobair Younossi .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-71 |
Machine learning-enabled continuous scor.. | Janani Iyer .. | .. | Metabolism, alcohol and toxicity.. | - - |
| THU-72 |
MARC1 and HSD17B13 variants have protect.. | Marcin Krawczyk .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-72 |
A lower cut-off of liver stiffness measu.. | Sagnik Biswas .. | Anshuman Elhence, Abhinav Anan.. | Metabolism, alcohol and toxicity.. | - - |
| THU-73 |
The impact of fatigue on mortality of pa.. | Zobair Younossi .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-73 |
Validation of the ADAPT score for the di.. | Arun Sanyal .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-73 |
High prevalence of multi-organ steatosis.. | Nicole Eichert .. | Gibbons K, Hamin A, Deelchand .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-74 |
Obeticholic acid reduces hepatic matrix .. | Marta Cagna .. | Giuseppina Palladini, Laura G... | Metabolism, alcohol and toxicity.. | - - |
| THU-74 |
Metabolic dysfunction-associated fatty l.. | María Del Barrio Azaceta .. | P. IRUZUBIETA, R. ALLER, J.M. .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-74 |
Plasma TREM2, a novel non-invasive bioma.. | Charlotte Wernberg .. | .. | Metabolism, alcohol and toxicity.. | - - |
| THU-75 |
Changes in hepatic fat fraction as asses.. | Samuel Daniels .. | .. | Metabolism, alcohol and toxicity.. | - - |
| SAT-75 |
Evaluation of semisynthetic high-fat die.. | Ozren Majstorovic .. | .. | Metabolism, alcohol and toxicity.. | - - |
| FRI-75 |
Unbiased clustering of exhaled breath pr.. | Rohit Sinha .. | Paul Brinkman, Khalida Ann Loc.. | Metabolism, alcohol and toxicity.. | - - |
| THU-76 |
The metabolic dysfunction-associated fat.. | María Del Barrio Azaceta .. | P. IRUZUBIETA, R. ALLER, J.M. .. | Metabolism, alcohol and toxicity.. | - - |
Abstract
Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy
Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.
Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.
Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.
Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.
