EASL Congress 2023


21-24 June Vienna
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EASL Congress 2023


21-24 June Vienna
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TOP-40-YI Evaluation of albumin and midodrine vers.. Priti Jain .. R. MAIWALL, S.K. SARIN, M. SHA.. Cirrhosis and complications.. - -
TOP-41-YI Randomised controlled trial of intraveno.. Tabish Mohammad .. .. Cirrhosis and complications.. - -
TOP-42 Yaq-001, a non-absorbable, engineered ca.. Jinxia Liu .. .. Cirrhosis and complications.. - -
TOP-43 Natural history of patients with NAFLD-a.. Rafael Paternostro .. .. Cirrhosis and complications.. - -
TOP-44-YI Nutritional therapy improves minimal hep.. Sudhir Maharshi .. BarjeshChanderSharma, Sanjeev .. Cirrhosis and complications.. - -
TOP-45 The effect of precipitating factors for .. Kevin Moore .. Zunaira Zafar, Nikolaos T. Pyr.. Cirrhosis and complications.. - -
TOP-46-YI The role of Toll-like receptor 4 in ammo.. Annarein Kerbert .. .. Cirrhosis and complications.. - -
TOP-48 Predictors and management of post-bandin.. Maria De Brito Nunes .. Matthias Knecht, Reiner Wiest,.. Cirrhosis and complications.. - -
TOP-49-YI Increased level of presepsin in patients.. Alberto Zanetto .. .. Cirrhosis and complications.. - -
TOP-50 Swarm hunting of virus-specific CD8 T ce.. Ariane Eceiza Tenreiro .. M. Dudek, D. Wohlleber, P. Kn.. Basic Science.. - -
TOP-51 Neoadjuvant PD-1 blockade with Pembroliz.. Hao Feng .. .. General Hepatology.. - -
TOP-52 Graft steatosis and donor diabetes melli.. Milan Sonneveld .. .. General Hepatology.. - -
TOP-53 Rheostat function of liver sinusoidal en.. Anna Fürst .. .. Basic Science.. - -
TOP-54-YI Health-related quality of life in a popu.. Helle Lindholm Schnefeld .. .. General Hepatology.. - -
TOP-55 Clinical features of portal hypertension.. Lukas Burghart .. .. General Hepatology.. - -
TOP-57 Long-term efficacy and safety of odevixi.. Ekkehard Sturm .. .. General Hepatology.. - -
TOP-58-YI Metabolomic profiles facilitate differen.. Bernhard Scheiner .. Georg Semmler, Oleksandr Petre.. General Hepatology.. - -
TOP-59-YI Two-year follow-up of liver grafts from .. Margherita Saracco .. .. General Hepatology.. - -
TOP-60 Bacteriophage therapy against pathologic.. Masataka Ichikawa .. Nobuhiro Nakamoto, Sharon Kred.. Immune-mediated and cholestatic diseases.. - -
TOP-61 Long-term prospective follow-up of a pri.. Conrado Fernandez-Rodriguez .. .. Immune-mediated and cholestatic diseases.. - -

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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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