EASL Congress 2023


21-24 June Vienna
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EASL Congress 2023


21-24 June Vienna
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LBP-21 A global research priority agenda to adv.. Jeffrey Lazarus .. Henry E. Mark, Alina M. Allen,.. Public Health.. - -
LBP-22 Twelve-week treatment with BOS-580, a no.. Rohit Loomba .. Kris Kowdley, Jose Rodriguez, .. Metabolism, alcohol and toxicity.. - -
LBP-23 Improving hepatitis B screening and link.. Anna Mageras .. Eric Woods, Brooke Wyatt, Rebe.. Public Health.. - -
LBP-24 Safety and efficacy of anti-pre-S1 domai.. Junqi Niu .. .. Viral Hepatitis.. - -
LBP-25 Concurrent nivolumab and external beam r.. Joong-Won Park .. .. Liver tumours.. - -
LBP-26 Evaluation of noninvasive tests to ident.. Mary Rinella .. .. Metabolism, alcohol and toxicity.. - -
LBP-27 Evaluation of the hepatitis B virus live.. Armando Andres Roca Suarez .. Barbara Testoni, Arianna Batti.. Basic Science.. - -
LBP-28 Phase 2a study of CM-101, a CCL24 neutra.. Rifaat Safadi .. .. Metabolism, alcohol and toxicity.. - -
LBP-29 Predictors of long-term mortality after .. Alessia Siribelli .. .. Viral Hepatitis.. - -
LBP-30-YI A new risk model outperforms FIB-4 when .. Rickard Strandberg .. Mats TalbäckNiklas HammarHanne.. Public Health.. - -
LBP-33-YI Investigating the potential of the prima.. Sara Teles .. .. Basic Science.. - -
LBP-34 Modelling intrahepatic bile duct morphog.. Iona Thelwall .. .. Basic Science.. - -
LBP-35 Long-term maintenance of response and im.. Richard Thompson .. .. Immune-mediated and cholestatic diseases.. - -
TOP-36 Liver cell-type specific molecular signa.. Martin Rnn Madsen .. Mathias B. Mllerhj, Mikkel P. .. Basic Science.. - -
LBP-36 Oral vancomycin induces remission in PSC.. Palak Trivedi .. .. Basic Science.. - -
LBP-37 Intestinal bacterial vesicles cause fibr.. Atsunori Tsuchiya .. .. Basic Science.. - -
TOP-37-YI Does sex influence the development of sa.. Katia Sayaf .. Katia Sayaf, Ilaria Zanotto, D.. Basic Science.. - -
LBP-38 Preliminary safety and antiviral activit.. Man-Fung Yuen .. .. Viral Hepatitis.. - -
TOP-38 Gut viral and bacterial alterations modu.. Jasmohan S Bajaj .. .. Basic Science.. - -
TOP-39-YI Tissue resident NK NTCP- transplanted to.. Johnny Amer .. .. Basic Science.. - -

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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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