21-24 June Vienna
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Deciphering the cellular and molecular d.. | Lingyun Zhang .. | .. | Liver tumours.. | - - |
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Spatial lipidomics reveal dysregulated s.. | Aleksandra Gruevska .. | Fiona Oakley, Jack Leslie, Der.. | Basic Science.. | - - |
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An algorithm for simplified hepatitis C .. | Ming-Lung Yu .. | .. | Viral Hepatitis.. | - - |
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RBD1016 a novel anti-HBV GalNAc-siRNA d.. | Li Ming Gan .. | .. | Viral Hepatitis.. | - - |
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Cyclophilin inhibition exhibits preventi.. | Una Rastovic .. | Sara Campinoti1,2, & Una Rasto.. | Basic Science.. | - - |
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Evaluating utilization and management of.. | Stuart C Gordon .. | .. | Viral Hepatitis.. | - - |
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HBV infection reshapes host chromatin ac.. | Vincenzo Alfano .. | .. | Viral Hepatitis.. | - - |
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Differential hepatoprotective effects of.. | Malte H. Nielsen .. | Susanne E. Pors, Jacob Nhr-Mel.. | Liver tumours.. | - - |
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Hepatic stellate cell-derived extracellu.. | Sara Campinoti .. | Lai Wei, Sara Campinoti, Bruna.. | Basic Science.. | - - |
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Capillarization of tumor endothelial cel.. | Pin-Hung Lin .. | Cheng-hsueh Tsai, Ian Liau, Hu.. | Liver tumours.. | - - |
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Identification of unique liver NK cells .. | Boris Beudeker .. | .. | Viral Hepatitis.. | - - |
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Concomitant use of proton pump inhibitor.. | Maria Buti .. | .. | Viral Hepatitis.. | - - |
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Impact of pegylated interferon-alpha in .. | Maura Dandri .. | .. | Viral Hepatitis.. | - - |
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Sofosbuvir/Velpatasvir plus Ribavirin fo.. | Ti Wu .. | .. | Viral Hepatitis.. | - - |
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Anti-CD122 antibody restores specific CD.. | Stéphanie Lacotte .. | .. | Liver tumours.. | - - |
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Selective RNF41 restoration in hepatic m.. | Alazne Moreno-Lanceta .. | .. | Basic Science.. | - - |
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Therapeutic effect of recombinant human .. | Norifumi Kawada .. | Pham Minh Duc, Le Thi Thanh Th.. | Basic Science.. | - - |
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Metabolic rewiring by increased mitochon.. | Naroa Goikoetxea .. | .. | Liver tumours.. | - - |
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Automated high-throughput image-based sc.. | Mara Klöhn .. | .. | Viral Hepatitis.. | - - |
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Efficacy of direct-acting antivirals in .. | Sofiia Gavrisheva .. | .. | Viral Hepatitis.. | - - |
Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy
Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.
Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.
Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.
Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.