28-31 May 2015 London
|FP-34||MEMBRANE-BOUND ACE AND ACE MRNA TRANSCRI..||Christof Ulrich ..||..||F1) Hypertension. Experimental...||Friday 29th May 2015|
|SP-34||CLINICAL AND MOLECULAR GENETIC CORRELATI..||Michael Kelly ..||Bodo B Beck, Matthais Wolf, Jo..||D) Genetic diseases and molecular geneti..||Saturday 30th May 2015|
|SP-35||IDENTIFICATION AND FUNCTIONAL STUDY OF A..||Renzo Bonofiglio ..||..||D) Genetic diseases and molecular geneti..||Saturday 30th May 2015|
|FP-36||OXIDATIVE STRESS IN CKD PATIENTS WITH UR..||Voineagu Lavinia ..||..||B) Cell signalling. Cell biology. Hormon..||Friday 29th May 2015|
|SP-36||THE FREQUENCY OF MEFV GENE MUTATIONS IN ..||Alpaslan Altunoglu ..||..||D) Genetic diseases and molecular geneti..||Saturday 30th May 2015|
|SP-38||IGA1-PROTEASE TREATMENT CLEARS MESANGIAL..||Sebastian Lechner ..||..||E) Renal pathology. Experimental and cli..||Saturday 30th May 2015|
|FP-39||STUDY OF THE EFFECT OF SOURCE OF MESENCH..||Rehab Ashour ..||Mohamed-Ahdy Saad1,2 , Mohame..||I1) Acute Kidney Injury - Experimental...||Friday 29th May 2015|
|SP-39||THERAPEUTIC ANGIOGENESIS IN RENAL ARTERY..||Alejandro Chade ..||Gene L. Bidwell III..||E) Renal pathology. Experimental and cli..||Saturday 30th May 2015|
|SP-41||THE USE OF BIOINFORMATICS TO INVESTIGATE..||Paul Rylance ..||..||E) Renal pathology. Experimental and cli..||Saturday 30th May 2015|
|SP-42||FREQUENCY OF T-CELL MEDIATED REJECTION I..||Bernadett Borda ..||..||E) Renal pathology. Experimental and cli..||Saturday 30th May 2015|
|FP-42||AUXIN INDUCES CELL PROLIFERATION IN AN E..||Valeria Cernaro ..||Maria Antonietta Medici, Giuse..||B) Cell signalling. Cell biology. Hormon..||Friday 29th May 2015|
|FP-43||IMPACT OF HEMODIAFILTRATION ON THE CONCE..||Homak Evgenija ..||Svetej MatejaRobert Ekart..||J2) Chronic Kidney Disease. Pathophysiol..||Friday 29th May 2015|
|SP-43||AUTOPHAGY-MEDIATED DELIVERY OF TISSUE FA..||ELENI FRANGOU ..||..||E) Renal pathology. Experimental and cli..||Saturday 30th May 2015|
|SP-44||MICRO-RNA REGULATED INTERACTIONS BETWEEN..||Janina Mller-Deile ..||..||H) Clinical Nephrology, primary and seco..||Saturday 30th May 2015|
|FP-44||COMPARISON OF TWO ASSAYS OF FIBROBLAST G..||Jerzy Chudek ..||Maria Bozentowicz-Wikarek, Ale..||J2) Chronic Kidney Disease. Pathophysiol..||Friday 29th May 2015|
|FP-45||DIET HIGHLY INFLUENCES THE DEVELOPMENT O..||Fabienne RAJAS ..||..||J6) Chronic Kidney Disease. Nutrition, i..||Friday 29th May 2015|
|FP-46||URINE AS SOURCE OF UNDIFFERENTIATED KIDN..||Fanny Oliveira Arcolino ..||..||N) Paediatric Nephrology...||Friday 29th May 2015|
|SP-46||AN IN VITRO MODEL OF THE GLOMERULUS..||Jack Tuffin ..||Gavin Welsh, Simon Satchell, M..||E) Renal pathology. Experimental and cli..||Saturday 30th May 2015|
|SP-47||ORAL TREATMENT WITH PBI-4547, A NOVEL FI..||Brigitte Grouix ..||Kathy Hince, Franois Sarra-Bou..||K2) Diabetes - Clinical studies...||Saturday 30th May 2015|
|FP-47||URINARY PROTEOMIC BIOMARKERS, A POWERFUL..||Martin Pejchinovski ..||Justyna Siwy, Jochen Metzger, ..||C) Renal development and cystic diseases..||Friday 29th May 2015|
Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy
Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.
Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.
Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.
Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.