21-24 June Vienna
THU-360-YI | MCC950 reduces glial cell activation and.. | Syed Afroz Ali .. | Dr. Ashok Kumar Datusalia.. | Cirrhosis and complications.. | - - |
FRI-360 | Elevated JAG1-NOTCH Signaling is Associa.. | Michael Trauner .. | .. | Immune-mediated and cholestatic diseases.. | - - |
SAT-360-YI | Skin-decellularized matrix-derived micro.. | Ashwini Vasudevan .. | .. | Basic Science.. | - - |
THU-361-YI | The pan-PPAR agonist lanifibranor decrea.. | Anneleen Heldens .. | .. | Cirrhosis and complications.. | - - |
WED-361 | Clostridioides difficile infection in pa.. | Olga Adriana Caliman-Sturdza .. | .. | Cirrhosis and complications.. | - - |
FRI-361 | Pyroptosis plays a key role in primary b.. | Linxiang Huang .. | Zi-Long Wang, Jia-Rui Zheng, Z.. | Immune-mediated and cholestatic diseases.. | - - |
SAT-361 | Autophagy regulates the generation and d.. | Hayoon Kim .. | .. | Basic Science.. | - - |
FRI-362-YI | Molecular signatures of treatment respon.. | Bastian Engel .. | .. | Immune-mediated and cholestatic diseases.. | - - |
SAT-362 | Development of intrahepatic bile ducts d.. | Eun Young Cho .. | Azra Memon, Siyeo Lee, Donghun.. | Basic Science.. | - - |
WED-362 | The prevalence and prognostic impact of .. | Alexandra Alexopoulou .. | .. | Cirrhosis and complications.. | - - |
FRI-363-YI | Loss of innate and adaptive effector lym.. | Hussain Syed .. | Greg Vallée1, Bishoi Aziz1, Ni.. | Immune-mediated and cholestatic diseases.. | - - |
SAT-363-YI | Excessive proliferation and vascular dam.. | Maxime De Rudder .. | .. | Basic Science.. | - - |
WED-363-YI | Comparison of prognostic value of sarcop.. | Shivam Gupta .. | B Mallick, SC Panigrahi, AC An.. | Cirrhosis and complications.. | - - |
WED-364 | Activation of the kynurenine pathway pot.. | Georgia Zeng .. | .. | Cirrhosis and complications.. | - - |
THU-364-YI | Glial transcriptional changes in experim.. | Wouter Claeys .. | .. | Cirrhosis and complications.. | - - |
SAT-364 | Conditioned medium from human allogeneic.. | Mustapha Najimi .. | Audrey Ginion, Marine Angé, Pa.. | Basic Science.. | - - |
WED-365 | A virtual reality-driving test to predic.. | Simon Johannes Gairing .. | E. M. Schleicher1,2, L. Kaps1,.. | Cirrhosis and complications.. | - - |
THU-365-YI | Ascites-resident innate-like CD8 T cells.. | Christian Niehaus .. | .. | Cirrhosis and complications.. | - - |
FRI-365-YI | Spatial transcriptomics reveals shared g.. | Mikal Jacob Hole .. | .. | Immune-mediated and cholestatic diseases.. | - - |
SAT-365 | Lineage tracing of hepatic stellate cell.. | Jingyan He .. | .. | Basic Science.. | - - |
Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy
Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.
Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.
Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.
Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.