EUROPEAN HEMATOLOGY ASSOCIATION

18th Congress of EHA

 

13-16 June 2013 STOCKHOLM
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EUROPEAN HEMATOLOGY ASSOCIATION

18th Congress of EHA

 

13-16 June 2013 STOCKHOLM
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posters found | 632
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-P-623 MRD LEVEL ANALYSIS IN ADULT ALL PATIENTS.. Cyril álek .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-624 FLUDARABINE, ARA-C AND LIPOSOMAL DAUNORU.. Marino Clavio .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-626 CLINICAL OUTCOME OF T- ACUTE LYMPHOBLAST.. mariachiara abbenante .. Papayannidis C., Iacobucci I. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-627 ENCOURAGING SURVIVAL IN T-CELL ACUTE LYM.. Elena Parovichnikova .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-629 FOUR YEARS EXPERIENCE WITH HYPER-CVAD TR.. Piotr Kozlowski .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-631 ADULT MIXED-PHENOTYPE ACUTE LEUKEMIA ACC.. Claudia Moreira .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-632 INTEGRATING ALTERNATIVE DONORS ALLOWS BE.. Barbara Forno .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-633 OBESITY, INSULIN RESISTANCE AND ADIPOKIN.. Trkiz Grsel .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-634 ZAP70 GENE EXPRESSION MAY BE A PROGNOSTI.. Bing Xu .. Guoshu Chen, MD, Pengcheng Shi.. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-638 EFFECTS OF PROPHYLACTIC CRANIAL RADIOTHE.. Gonul Aydogan .. .. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-639 THE IMPACT OF RISK STRATIFICATION BY EAR.. BEN ABDENNEBI Yosr .. Lamia Aissaoui , Hend Ben Neji.. Acute lymphoblastic leukemia - Biology 2.. 15.06.2013 17:45
-P-641 IDENTIFICATION OF NOVEL GENETIC ALTERATI.. Marco Togni .. Riccardo Masetti, Annalisa Ast.. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-643 ALTERED GENES DOWNSTREAM OF MYCN IN ACUT.. Li-Jing SHEN .. .. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-645 EXPRESSION, REGULATION AND FUNCTIONAL RO.. Deog-Yeon Jo .. .. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-646 INTERLEUKIN-3 RECEPTOR ALPHA CHAIN (CD12.. Hanan Alwakeel .. Iman Maher Mansour, Nahed abd.. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-647 EFFECTS OF B-MYB ABERRANT EXPRESSION ON .. SANDRA DOLZ GIMÉNEZ .. .. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-648 MUTATIONS IN RUNX1 AND NPM1 COMBINED WIT.. Katya Gancheva .. .. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-649 PROGNOSTIC VALUE OF B-MYB AND ITS REGULA.. Marta Llop García .. .. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-651 CLINICAL AND HEMATOLOGICAL FEATURES OF A.. marion eveillard .. .. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
-P-653 IMPACT OF THE E3 UBIQUITIN LIGASE TRAF2 .. Sebastian Scholl .. .. Acute lymphoblastic leukemia - Clinical .. 15.06.2013 17:45
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Abstract

Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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