The Digital International Liver Congress™ 2021


23-26 June 2021 Virtual Conference
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PO-147 Hepatitis B vaccine NON-RESPONDERS show .. Laureen Pohl .. .. General hepatology.. - -
PO-153 Prevalence and origin of rare HCV Genoty.. Julia Dietz .. .. Viral hepatitis.. - -
PO-159 Target engagement and evidence of effica.. Vlad Ratziu .. .. Metabolism, alcohol and toxicity.. - -
PO-167 Derivation and validation of the NAFLD c.. Christian Labenz .. .. Metabolism, alcohol and toxicity.. - -
PO-175 A cell-based cccDNA reporter assay combi.. Gatan Ligat .. .. Viral hepatitis.. - -
PO-186 Real-world experience of mTOR inhibitors.. Pil Soo Sung .. .. General hepatology.. - -
PO-187 Non-malignant portal vein thrombi in pat.. Ellen Driever .. Fien A. von Meijenfeldt, Jelle.. Cirrhosis and complications.. - -
PO-190 Patients with LIVER CIRRHOSIS - SATISFAC.. Marie Louise Sjoedin Hamberg .. Lene Dupont, Marthe Jnsson, Ha.. General hepatology.. - -
PO-195 Role of Mcpip1 in obesity-induced hepati.. Natalia Pydyn .. .. Metabolism, alcohol and toxicity.. - -
PO-196 Chronic liver damage favours induction o.. Akshaya Srikanth .. Umesh TharehalliReinhold Schir.. Liver tumors.. - -
PO-205 A new prediction equation for estimating.. Bruna Cherubini Alves .. Moiséli Moreira Luchi da Cruz;.. General hepatology.. - -
PO-210 A Dose-Finding, Positive Proof of Concep.. Kris Kowdley .. .. Immune-mediated and cholestatic diseases.. - -
PO-212 Early Renal Dysfunction Post Liver Trans.. Ramzi Hassouneh .. .. General hepatology.. - -
PO-216 Liver resident Natural Killer cells are .. Adrian Kuipery .. .. General hepatology.. - -
PO-218 Incidence and resolution of steatohepati.. Yiwen Shi .. Xiu-Juan Chang, Jing Wang, Hua.. Viral hepatitis.. - -
PO-223 Precision-cut liver slices as a dynamic .. Liza Dewyse .. V. De Smet, H. Reynaert, L. A... General hepatology.. - -
PO-230 Semaglutide in patients with non-alcohol.. Sven Francque .. Sven Francque, Mette S. Kjaer,.. Metabolism, alcohol and toxicity.. - -
PO-231 Effect of subcutaneous semaglutide on qu.. Manuel Romero Gomez .. Manuel Romero Gomez, Andrew Au.. Metabolism, alcohol and toxicity.. - -
PO-235 Combined PD-1 blockade plus IL-15 treatm.. Julia Peña Asensio .. H.Calvo, J.Miquel, E.Sanz de V.. General hepatology.. - -
PO-240 Identification of a CD8 T cell populatio.. Shirin Nkongolo .. .. General hepatology.. - -

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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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