International Liver Congress™ 2022


22-26 June, 2022 London
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posters found | 1471
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SAT-144 Novel thyroid hormone receptor-beta agon.. Andrea Marco Caddeo .. M. A. KOWALIK, M. SERRA. S. R.. Metabolism, alcohol and toxicity.. - -
SAT-145 Safety and pharmacokinetics (PK) of sing.. Hakim Charfi .. .. Metabolism, alcohol and toxicity.. - -
FRI-146 Hepatic angiocrine HGF attenuates liver .. Jianye Wang .. SARAH SCHULZE, VICTOR OLSAVSZK.. Basic Science.. - -
SAT-146 A MEDITERRANEAN DIET INTERVENTION has BE.. Laura Haigh .. .. Metabolism, alcohol and toxicity.. - -
FRI-147 Bisphosphonate-loaded nanogels attentuat.. Leonard KAPS .. .. Basic Science.. - -
FRI-148 Preclinical evaluation of the calpain in.. Ravi Rajagopalan .. .. Basic Science.. - -
FRI-149 Experimental fibrosis alters matrix-boun.. TOSHIFUMI SATO .. Bashar Al Matour, Jiang Li, Mi.. Basic Science.. - -
FRI-150 Hepatocyte cell-specific deletion of cat.. Maria Fernandez-Fernandez .. P. Ruiz-Blazquez, V. Pistorio,.. Basic Science.. - -
FRI-151 The therapeutic potential of alpha v int.. Syedia Rahman .. .. Basic Science.. - -
THU-151 Altered fecal microbiome and metabolome .. Yue Shen .. .. Basic Science.. - -
SAT-151 CD44 plays critical role in liver regene.. Wan Seob Shim .. Hyun Young Kim, Sang Kyum Kim .. Basic Science.. - -
THU-152 The therapeutic effect of Lactobacillus .. DongYun Kim .. .. Basic Science.. - -
FRI-152 Dual inhibition of integrins alpha-v/bet.. Philipp Knigshofer .. J Schaub, K Brusilovskaya, BS .. Basic Science.. - -
SAT-152 Development of ECM mimicking 3D-hydrogel.. Nathan Carpentier .. .. Basic Science.. - -
THU-153 Stool microbiota, compared to salivary m.. I. Jane Cox .. Marcela Peña Rodriguez, Andrew.. Basic Science.. - -
FRI-153 Dual roles of PSMP/MSMP in the progressi.. Shaoping She .. .. Basic Science.. - -
SAT-153 Three-dimensional conditions in a perfus.. Sara Campinoti .. Negin Goudarzi, Bruna Almeida,.. Basic Science.. - -
FRI-154 NKT cells promote both type 1 and type 2.. Sofia Mayans .. Julia Nilsson, Maria Hrnberg, .. Basic Science.. - -
SAT-154 Knockdown of Glyoxylate reductase/hydrox.. Viktoriia Iakovleva .. .. Basic Science.. - -
THU-154 The gut virome in non-alcoholic fatty li.. Hau-Tak Chau .. Wai-Kay SetoDepartment of Medi.. Basic Science.. - -

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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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