International Liver Congress™ 2022


22-26 June, 2022 London
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posters found | 1471
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THU-12 Antibody response to gut microbiome bact.. Antonella Putignano .. .. Metabolism, alcohol and toxicity.. - -
SAT-13 Targeted metabolomics reveals alteration.. Mikkel Werge .. .. Metabolism, alcohol and toxicity.. - -
FRI-13 Human paracetamol hepatotoxicity is miti.. Martin Vandeputte .. K. Morgan1, M. Vandeputte1, K... Metabolism, alcohol and toxicity.. - -
THU-13 Socio-economic factors and healthcare se.. Joshua Lambert .. Nikhil VergisMichael AllisonAn.. Metabolism, alcohol and toxicity.. - -
THU-14 Sex-related differences in outcomes in a.. Aaminah Mohammed .. Nora Khattab, Clive D Jackson,.. Metabolism, alcohol and toxicity.. - -
FRI-15 Ten-year single center experience in hep.. Ozan Sarikaya .. &304;lker Turan, Fulya Gn&351;.. Metabolism, alcohol and toxicity.. - -
SAT-15 Deletion of ATR in hepatocytes improves .. Maeva Saroul .. .. Metabolism, alcohol and toxicity.. - -
THU-15 Influence of comorbidities and lifestyle.. Karen Dombestein Elde .. .. Metabolism, alcohol and toxicity.. - -
THU-16 Patient and system-level factors underli.. Jasmohan S Bajaj .. .. Metabolism, alcohol and toxicity.. - -
SAT-16 The AXL inhibitor bemcentinib reduces i.. Sturla M. Groendal .. .. Metabolism, alcohol and toxicity.. - -
FRI-17 The association between chronic Colchici.. Michal Carmiel .. .. Metabolism, alcohol and toxicity.. - -
SAT-17 Human Liver Organoids with myeloid linea.. Milad Rezvani .. Milad Rezvani1,2,3, Kyle Lewis.. Metabolism, alcohol and toxicity.. - -
THU-17 24-Norursodeoxycholic acid ameliorates e.. Christoph Grander .. .. Metabolism, alcohol and toxicity.. - -
FRI-18 Inhibition of C-C motif chemokine recept.. Eline Geervliet .. Ralf Weiskirchen, Ruchi Bansal.. Metabolism, alcohol and toxicity.. - -
THU-18 Impact of sex and recurrence in the prog.. Jordi Gratacós-Gines .. .. Metabolism, alcohol and toxicity.. - -
SAT-19 Increased liver content of omega-3-deriv.. Cristina López-Vicario .. .. Metabolism, alcohol and toxicity.. - -
FRI-19 Murine intrahepatic regulatory t cells m.. Ada Kurt .. .. Metabolism, alcohol and toxicity.. - -
THU-19 Hepatocyte-derived biomarkers concentrat.. Laure Elkrief .. .. Metabolism, alcohol and toxicity.. - -
SAT-20 Factors associated with increased gut pe.. Roberta Forlano .. .. Metabolism, alcohol and toxicity.. - -
FRI-20 Place of steroids and prognosis factors .. Eleonora De Martin .. .. Metabolism, alcohol and toxicity.. - -

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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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