EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER

International Liver Congress™ 2022

 

22-26 June, 2022 London
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FRI-76 The pericellular basement of the hepatoc.. Ida Lnsmann Lnsmann .. .. Metabolism, alcohol and toxicity.. - -
SAT-76 Tyrosinase mutations, a novel predisposi.. Kaushalya Kulathunga .. .. Metabolism, alcohol and toxicity.. - -
FRI-77 A re-appraisal of the diagnostic perform.. Chul-min Lee .. .. Metabolism, alcohol and toxicity.. - -
THU-77 Assessment of the prevalence of nonalcoh.. Emily Truong .. G. Cook-Wiens, N. Alkhouri, an.. Metabolism, alcohol and toxicity.. - -
SAT-78 Recapitulating insulin resistance in a 3.. Radina Kostadinova .. L. Hoelting1, S. Hutter1, A. M.. Metabolism, alcohol and toxicity.. - -
THU-78 Coagulation imbalance is associated with.. Rosa Lombardi .. .. Metabolism, alcohol and toxicity.. - -
FRI-78 Cost utility analysis for screening for .. Mazen Noureddin .. .. Metabolism, alcohol and toxicity.. - -
FRI-79 Free Light Chains as a potential biomark.. Antonio Liguori .. .. Metabolism, alcohol and toxicity.. - -
SAT-79 Novel endosomal trafficking adaptor for .. Karsten Motzler .. Karsten Motzler, K. Nalbach, R.. Metabolism, alcohol and toxicity.. - -
THU-79 Presence of two or more metabolic risks .. Huiyul Park .. .. Metabolism, alcohol and toxicity.. - -
THU-80 Pregnancy as a unique opportunity to ide.. Tatyana Kushner .. T Kushner1,2, S. Johnson1, M. .. Metabolism, alcohol and toxicity.. - -
FRI-80 12-week very low calorie diet in NAFLD i.. Jadine Scragg .. .. Metabolism, alcohol and toxicity.. - -
SAT-80 Enzymatic activity dysfunction of the mi.. Alberto García Picazo .. .. Metabolism, alcohol and toxicity.. - -
FRI-81 Signature of circulating hepatic protein.. Olivier Govaere .. .. Metabolism, alcohol and toxicity.. - -
SAT-81 Lipid-induced phenotypic differences in .. Ruth Walker .. Michalina Zatorska, Jose Luis .. Metabolism, alcohol and toxicity.. - -
FRI-82 Peripheral blood mononuclear cells mitoc.. Eileen Yoon .. .. Metabolism, alcohol and toxicity.. - -
SAT-82 Regulation of NEAT1 in NAFLD by RNA-bind.. Lisa Ahne .. .. Metabolism, alcohol and toxicity.. - -
THU-82 Genetic risk of fatty liver disease and .. Helene Gellert-Kristensen .. Brge G. Nordestgaard, Anne Tyb.. Metabolism, alcohol and toxicity.. - -
SAT-83 Anti-inflammatory effect of simvastatin-.. Han Seul ki .. .. Metabolism, alcohol and toxicity.. - -
FRI-83 Comparison of diagnostic performance bet.. Dae Won JUN .. .. Metabolism, alcohol and toxicity.. - -
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Abstract

Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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