26-28 September 2019 Seville
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26-28 September 2019 Seville
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P05-18-YI NEDDylation inhibition as a new potentia.. Marina Serrano-Macia .. M. Serrano-Macia, M. Azkargort.. Metabolism, alcohol and toxicity.. - -
P03-18-YI Differential therapeutic effects of sing.. Sander Lefere .. S. Lefere, T. Puengel, J. Hund.. Metabolism, alcohol and toxicity.. - -
P04-18 Ablation of High mobility group box-1 in.. Natalia Nieto .. H. Gaskell, H. Han, R. Desert.. Metabolism, alcohol and toxicity.. - -
P02-18-YI Transcriptomic and epigenetic characteri.. Antonio Gil-Gomez .. A. Gil-Gomez, A. Rojas, R. Mun.. Metabolism, alcohol and toxicity.. - -
P01-18 In patients with Nonalcoholic Fatty Live.. Paola Casciato .. P. Casciato, E. Mauro, C. Berm.. Metabolism, alcohol and toxicity.. - -
P01-19 Efficacy and Safety of Saroglitazar in M.. Sujit Chaudhuri .. S. Chaudhuri.. Metabolism, alcohol and toxicity.. - -
P02-19-YI Osteopontin deficiency promotes liver se.. Beatriz Gómez Santos .. B. Gómez Santos, M. Ruiz de Ga.. Metabolism, alcohol and toxicity.. - -
P04-19-YI Fibrosis impact on quality of life in no.. Jesus Funuyet-Salas .. J. Funuyet-Salas, M.A Pérez-Sa.. Metabolism, alcohol and toxicity.. - -
P03-19 GLI-3 mutation influences weight gain, g.. Jiawei Li .. J. Li, P. Cordero, A. Solanki,.. Metabolism, alcohol and toxicity.. - -
P05-19 Predictors of high shear wave elastograp.. Abdel-Aziz Shaheen .. Kiarash Riazi, Wendy Schaufert.. Metabolism, alcohol and toxicity.. - -
P06-19-YI PNPLA3 rs738409 Gene Variant Aggravates .. Kenneth Iden Zheng .. DQ Sun, KI Zheng, HL Ma, WY Li.. Metabolism, alcohol and toxicity.. - -
P05-20 Establishment of an novel non-alcoholic .. Eiketsu Sho .. E. Sho, J. Chen, S. Jiang, P. .. Metabolism, alcohol and toxicity.. - -
P06-20 Myeloid Cells-Derived Osteopontin Protec.. Natalia Nieto .. H. Han, X. Ge, H. GASKELL, D. .. Metabolism, alcohol and toxicity.. - -
P04-20 Metabolic caracterization of hepatocellu.. Claudia Oliveira .. S. Granja, A. Longatto-Filho, .. Metabolism, alcohol and toxicity.. - -
P03-20-YI Effect of treatment with dulaglutide on .. Ekaterina Liusina .. P. Bogomolov, E. Liusina, O. N.. Metabolism, alcohol and toxicity.. - -
P02-20 Actions of the protease fibroblast activ.. Mark Gorrell .. H. Zhang, S. Chowdhury, M. Xia.. Metabolism, alcohol and toxicity.. - -
P01-20-YI Utility of applying age-adjusted FIB-4 c.. Stefano Ciardullo .. S. Ciardullo, E. Muraca, S. Pe.. Metabolism, alcohol and toxicity.. - -
P01-21 Impact of FAT10 on PPAR-alpha downregula.. Ludivine Clavreul .. L. Clavreul, A. Cotte, B. Stae.. Metabolism, alcohol and toxicity.. - -
P02-21 The Vanin 1-Cysteamine pathway regulates.. Olivier Govaere .. O. Govaere, J. Palmer, S. Pete.. Metabolism, alcohol and toxicity.. - -
P03-21-YI Effect of metformin therapy on the clini.. Saidrakhim Lukmonov .. S. Lukmonov, U. Kurbankulov, O.. Metabolism, alcohol and toxicity.. - -
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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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