ESMO 22nd World Congress on Gastrointestinal Cancer


1-4 July 2020 Barcelona
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ESMO 22nd World Congress on Gastrointestinal Cancer


1-4 July 2020 Barcelona
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P-144 Infigratinib versus gemcitabine plus cis.. Ghassan Abou-Alfa .. .. Clinical Bilary Tract Cancer.. - -
P-145 CT-based texture analysis using radiomic.. Kiyotaka Kawaguchi .. .. Clinical Colon Cancer.. - -
P-146 A genetic custom-made in vivo drug scree.. Nahuel Villegas .. .. Clinical Colon Cancer.. - -
P-147 Efficacy and safety data of trifluridine.. María Amor Urbano .. Victoria Aviñó Tarazona, Marta.. Clinical Colon Cancer.. - -
P-150 Khorana and PROTECHT scores in predictin.. Sara Dmaso .. .. Clinical Pancreatic Cancer.. - -
P-151 The impact of adjuvant chemotherapy regi.. Soraia Lobo-Martins .. .. Clinical Colon Cancer.. - -
P-152 The impact of 2nd-line treatment after 1.. Maria Bensi .. .. Clinical Pancreatic Cancer.. - -
P-153 Novel ultrasonographic scoring system of.. Rika Saito .. .. Clinical Colon Cancer.. - -
P-154 Actionable targets by tumor genomic prof.. Francesca Avogadri .. .. Clinical Bilary Tract Cancer.. - -
P-155 Efficacy of somatostatin analogues in th.. Rafael Correa Cano .. .. Others ( Including GIST and Anal Cancer .. - -
P-156 A phase Ib\II study of cetuximab and pem.. Christos Fountzilas .. .. Clinical Colon Cancer.. - -
P-157 Incidence and survival of intestinal sof.. Shuai Wang .. Apoorva Jayarangaiah, Mariuxi .. Others ( Including GIST and Anal Cancer .. - -
P-158 Clinical impact of oral intake in third-.. Takatsugu Ogata .. .. Clinical Gastric Cancer.. - -
P-160 A phase II study of resection followed c.. Takanori Watanabe .. Naotoshi Sugimoto, Hiroshi Tam.. Clinical Colon Cancer.. - -
P-161 Efficacy of third-line anti-EGFR-based t.. Raffaella Vivolo .. .. Clinical Colon Cancer.. - -
P-162 Perioperative capecitabine-oxaliplatin c.. Arezki Arab .. .. Clinical Gastric Cancer.. - -
P-163 Systemic chemotherapy for previously tre.. Taiko Nakazawa .. .. Others ( Including GIST and Anal Cancer .. - -
P-164 The role of response as a predictor of i.. Marta Chiaravalli .. .. Clinical Pancreatic Cancer.. - -
P-166 Baseline radiomics features in metastati.. Annunziato Anghelone .. .. Clinical Colon Cancer.. - -
P-167 Impact of testosterone on sexual functio.. Annika Svanstrm Rjvall .. Christian BuchliAngelique Flte.. Clinical Rectal Cancer.. - -

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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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