TRISOMY 21 RESEARCH SOCIETY

3rd International Conference

 

6 - 9 June 2019 Barcelona
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TRISOMY 21 RESEARCH SOCIETY

3rd International Conference

 

6 - 9 June 2019 Barcelona
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PosterSessionOnline
   1-53 | 56-158 |
posters found | 38
Poster no.
Poster/abstract title
Author
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Presentation date and time
PO-56 Induced Pluripotent Stem Cells as a Tool.. Sarah Lee .. .. Poster Session 1.. - -
PO-63 NEW HITS IDENTIFIED IN A DRUG SCREENING .. Fiorenza Stagni .. .. Poster session 2 Nano-symposium 4 | 17:.. - -
PO-64 PRENATAL PHARMACOTHERAPY WITH A BDNF MIM.. Marco Emili .. .. Poster session 2 Nano-symposium 4 | 17:.. - -
PO-76 THE EARLY ONSET OF BRAIN INSULIN RESISTA.. Marzia Perluigi .. Tramutola A, Arena A, Di Domen.. Poster Session 2.. - -
PO-78 MOLECULAR CROSSTALK BETWEEN DOWN SYNDROM.. Wileidy Gomez .. Vinicius Maracaja, Valentina P.. Poster Session 2.. - -
PO-79 Investigating The Role Of Genes Other Th.. Paige Mumford .. Dr Justin ToshEllie RhymesDr S.. Poster Session 2.. - -
PO-80 Chronic UPR activation in Down syndrome .. Chiara Lanzillotta .. ILARIA ZULIANI; ANTONELLA TRAM.. Poster Session 2.. - -
PO-91 The Norwegian Down Syndrome and Dementia.. Ellen Melbye Langballe .. Frode Kibsgaard Larsen, Ingrid.. Poster Session 2.. - -
PO-95 CSF NPTX2 AS A SYNAPTIC BIOMARKER OF ALZ.. Meifang Xiao .. .. Poster Session 2.. - -
PO-97 THE LIFE-DSR STUDY: A 3-YEAR LONGITUDINA.. James A Hendrix .. Please see listed authors in p.. Poster Session 2.. - -
PO-98 Human iPSC-Derived Down Syndrome Astrocy.. Blandine Ponroy .. .. Poster Session 2.. - -
PO-100 Partial trisomy 21 map: ten cases furthe.. Allison Piovesan .. .. Poster Session 2.. - -
PO-119 Mitochondrial fusion and function are el.. Beverly Rothermel .. Viktoriia KyrychenkoValentina .. Poster session 3 Nano-symposium 1 |18:3.. - -
PO-130 Relationship Between Apgar Scores and Lo.. Laura Del Hoyo Soriano .. Tracie Rosser, Debra Hamilton,.. Poster Session 3.. - -
PO-137 Word-Word relationships in Down syndrome.. Julia Beatriz Barrón-martínez .. Arias-Trejo, N.; Salvador-Cruz.. Poster Session 3.. - -
PO-143 Hemodynamic profile of adults with Down .. Emilia Roy Vallejo .. .. Poster Session 3.. - -
PO-153 METABOLIC-RELATED ALTERATION OF PROTEIN .. Fabio Di Domenico .. I. Zuliani, A. Tramutola, E. B.. Poster Session 3.. - -
PO-158 Apigenin as a Candidate Prenatal Treatme.. Faycal Guedj .. .. Poster Session 3.. - -
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Abstract

Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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