EUROPEAN ASSOCIATION FOR THE STUDY OF THE LIVER

Digital NAFLD Summit 2021

 

16-17 September 2021
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   10-87 | 88-151 | 153-186 | 187-237 | 239-269 |
posters found | 93
Poster no.
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PO-187 INT-747 ameliorates NASH pathogenesis by.. Balasubramaniyan Vairappan .. .. Basic Science.. - -
PO-190 Single-cell analysis of NAFLD induced by.. Fumihiko Takeuchi .. .. Basic Science.. - -
PO-193 Anti-inflammatory and anti-fibrotic effe.. DavidA. Fraser .. .. Basic Science.. - -
PO-197 Menopausal women with NAFLD show impaire.. Roberta Forlano .. .. Clinical Science.. - -
PO-203 4-methylpyrazole attenuates the developm.. Katharina Burger .. Finn Jung, Annette Brandt, Anj.. Basic Science.. - -
PO-205 Mitochondria-targeted antioxidant based .. Ricardo Amorim .. .. Basic Science.. - -
PO-206 The activation of Liver X Receptor alpha.. Gessica Lioci .. .. Basic Science.. - -
PO-207 Nonalcoholic steatohepatitis modifies li.. Helena Castañé .. .. Clinical Science.. - -
PO-208 A little is better than nothing: very lo.. Bernardo Stefanini .. .. Clinical Science.. - -
PO-215 A 3D in vitro throughput-based discovery.. Simon Strbel .. .. Basic Science.. - -
PO-220 Rising indication of non-alcoholic steat.. Laura Martínez Arenas .. Angela Carvalho-Gomes, Julia H.. Clinical Science.. - -
PO-221 TM6SF2/PNPLA3/MBOAT7 loss-of-function ge.. Miriam Longo .. .. Basic Science.. - -
PO-222 The I148M PNPLA3 variant mitigates Niaci.. Erika Paolini .. .. Clinical Science.. - -
PO-223 MAFLD definition underestimates the risk.. Marica Meroni .. .. Clinical Science.. - -
PO-225 Outcomes of postmenopausal women with no.. Chioma Izzi-Engbeaya .. .. Clinical Science.. - -
PO-229 Preclinical animal models for nonalcohol.. Kris Rutten .. .. Basic Science.. - -
PO-230 Targeting the pro-inflammatory phenotype.. Celia Martínez Sánchez .. .. Basic Science.. - -
PO-231 Cognitive dysfunction is associated with.. AnneCatrine Daugaard Mikkelsen .. Kristoffer Kjrgaard, Cecilie B.. Basic Science.. - -
PO-234 Assessment of systemic inflammation by 3.. Jiahui Li .. Marzanna Obrzut, Xin Lu, Kevin.. Clinical Science.. - -
PO-237 Gender differences in characteristics of.. Oyekoya Ayonrinde .. Phillip MELTON, Caryn ELSEGOOD.. Clinical Science.. - -
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Abstract

Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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