Translational research in viral hepatitis: Addressing the gaps for cur


23-25 January,2020 Athens
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Translational research in viral hepatitis: Addressing the gaps for cure


23-25 January,2020 Athens
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posters found | 30
Poster no.
Poster/abstract title
Presentation date and time
P01-1 Filling the gaps: HCV treatment at a nee.. Marianne Alanko Blomé .. .. Viral hepatitis.. - -
P02-1 Efficacy and safety of elbasvir/grazopre.. Pavel Bogomolov .. .. Viral hepatitis.. - -
P03-1 Therapy of hepatitis C in people who inj.. Sona Frankova .. .. Viral hepatitis.. - -
P06-1-YI Metabolic programming of exhausted CD8 T.. Frances Winkler .. .. Viral hepatitis.. - -
P04-1 The role of sphingolipids as potential b.. Georgios Grammatikos .. Aissa RhrigStefan Zeuzem.. Viral hepatitis.. - -
P05-1-YI Targeting hepatitis B virus with CRISPR/.. Maria Guadalupe Martinez .. .. Viral hepatitis.. - -
P04-2 Hepatitis C virus dysregulates polyamine.. Alexander Ivanov .. Natalia F. Zakirova, Olga A. K.. Viral hepatitis.. - -
P05-2-YI Reaching people who inject drugs most in.. Sotiris Roussos .. G. Kalamitsis, E. Cholongitas,.. Viral hepatitis.. - -
P06-2 A transient early HBV DNA increase durin.. Olympia Anastasiou .. .. Viral hepatitis.. - -
P03-2-YI Development of Bipolymer based novel Nan.. Prakash Gosain .. .. Viral hepatitis.. - -
P01-2-YI Development and Characterization of Oral.. Mani Bhargava .. .. Viral hepatitis.. - -
P02-2 hepatitis e virus infection among people.. Lawal Dahiru Rogo .. .. Viral hepatitis.. - -
P01-3-YI Antibody coated Liposomes for Transmucos.. Saurabh Bhargava .. Dr Vishal Bhargava.. Viral hepatitis.. - -
P02-3-YI HCV treatment with DAA in children and a.. Elena Egorova .. .. Viral hepatitis.. - -
P03-3-YI Lipid based Nanoparticulate system for e.. Priyanka Gosain .. Saurabh Bhargava.. Viral hepatitis.. - -
P05-3-YI Homocysteine mediated oxidative stress i.. Diptika Tiwari .. Rizwana Sultana, Purabi Deka B.. Viral hepatitis.. - -
P06-3-YI A CRISPR/Cas9 screen to identify host fa.. Noémie Oechslin .. .. Viral hepatitis.. - -
P04-3 HCV course, efficacy and safety of DAA t.. Abdourahman Jallow .. Bogomolov P.O., Bueverov A.O. .. Viral hepatitis.. - -
P06-4 Hepatitis b virus x protein is required .. Amir Shlomai .. .. Viral hepatitis.. - -
P04-4 After the achivement of sustained virolo.. Yoshiyasu Karino .. .. Viral hepatitis.. - -
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Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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