WORLD FEDERATION OF HEMOPHILIA

WFH 2012 World Congress

 

8-12 July, 2012 Paris, FRANCE
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WORLD FEDERATION OF HEMOPHILIA

WFH 2012 World Congress

 

8-12 July, 2012 Paris, FRANCE
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posters found | 439
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Tu-140 Differences in the Bleeding Phenotypes o.. Berthold Siegmund .. Hartmut Pollmann.. Other Treatment Modalities.. - -
Mo-140 Duplications Xq28 and Hemophilia are que.. Catherine Costa .. Rothschild CBieth EBriand AMet.. Molecular Genetics of Bleeding Disorders.. - -
Mo-141 Spectrum of mutations in 407 unrelated h.. Guillerm Erell .. .. Molecular Genetics of Bleeding Disorders.. - -
Mo-143 A third rearrangement caused by homologo.. Behnaz Pezeshkpoor .. .. Molecular Genetics of Bleeding Disorders.. - -
Mo-145 Inversion 22 in Hemophilia A in the Nort.. Praveen Kumar .. Nuzhat Husain, Nuzhat Jahan Fa.. Molecular Genetics of Bleeding Disorders.. - -
We-145 Genotype-phenotype Correlation in Hemoph.. jinyoung choi .. .. Inhibitors Pathogenesis, Prevention and .. - -
Tu-145 The method of concentration of blood clo.. Kate Kabaeva .. .. Other Treatment Modalities.. - -
Tu-146 A New Clinical Tool to Measure Balance a.. Cecily Bos .. .. Outcome Assessment.. - -
We-149 Prevalence of inhibitor antibodies in th.. Hassan Mahmoodi Nesheli .. .. Inhibitors Pathogenesis, Prevention and .. - -
Mo-149 INTRACELLULAR TRAFFICKING ANALYSIS OF C1.. JOHANNA MANTILLA CAPACHO .. Nathalie Enjolras, Claude Negr.. Molecular Genetics of Bleeding Disorders.. - -
We-150 USE OF FACTOR VIII CONCENTRATES IN LIFE-.. Hugh C Kim .. Hyun Woo Lee.. Inhibitors Pathogenesis, Prevention and .. - -
Tu-150 ADVATE HaEmophlia A Outome Database (AHE.. Gerald Spotts .. J. Oldenburg, I. Abraham, M. P.. Outcome Assessment.. - -
Mo-150 GENETICS DEFECTS IN VON WILLEBRAND DISEA.. Rosario Pérez Garrido .. Isabel Álvarez LaderasRamiro N.. Molecular Genetics of Bleeding Disorders.. - -
Mo-151 Absence of active F8 protein despite hig.. Behnaz Pezeshkpoor .. .. Molecular Genetics of Bleeding Disorders.. - -
Tu-151 A Post-Authorisation Safety Surveillance.. Yeu-Chin Chen .. Dr. Shin-Nan Cheng.. Outcome Assessment.. - -
We-151 Intracranial Hemorrhage (ICH) in a 5-yea.. Carvalho Manuela .. .. Inhibitors Pathogenesis, Prevention and .. - -
We-152 Prevalence of inhibitor in a prospective.. Florencia Tisi Baña .. Baques A, Candela M, Pérez bia.. Inhibitors Pathogenesis, Prevention and .. - -
Mo-152 IDENTIFICATION OF MUTATIONS ASSOCIATED W.. Serge PIERRE-LOUIS .. .. Molecular Genetics of Bleeding Disorders.. - -
Tu-152 Estimated Annual Infusion Volume Reducti.. josh epstein .. .. Outcome Assessment.. - -
Mo-153 The Canadian National Program for Hemoph.. Natalia Rydz .. Leggo J,Tinlin SJames PLillicr.. Molecular Genetics of Bleeding Disorders.. - -
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Abstract

Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy

Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.

Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.

Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.

Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.

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