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ESMO 17th World Congress on Gastrointestinal Cancer 2015

 

1 - 4 July 2015 Barcelona
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Discussion forum - ESMO 17th World Congress on Gastrointestinal Cancer 2015
    Topic - Basic Gastric Cancer

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Poster: 18
Visits: 39
Title: Desacetyl isovaltratum, an extract from Valeriana, induces G2/M phase arrest and apoptosis in gastric cancer cell lines
Authors: Bo Zhang ,
Centre: Hangzhou First Peoples Hospital

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DESACETYL ISOVALTRATUM, AN EXTRACT FROM VALERIANA, INDUCES G2/M PHASE ARREST AND APOPTOSIS IN GASTRIC CANCER CELL LINES

Bo Zhang
Thread initiator
Subspeciality
Reg: 6/18/2015 3:41:00 AM

Comment# 1

DI is a pure compound isolated from Valeriana, and the structure of DI has been well demonstrated. In this study, DI showed in vitro anti-cancer activity in gastric cell lines through the induction of G2/M phase arrest. Further study showed that DI promoted tubulin polymerization, which contributed to its G2/M phase arrest activity. Next, we will dedicate to explore the potential molecular target of DI, explicating the anti-cancer mechanism of this newly extracted natural product.

Comment added on 6/18/2015 3:41:00 AM 
     
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Most viewed poster for this congress
Poster: 98
Visits: 485
Title: LOCAL ADVANCED GASTRIC CANCER: OPTIMIZATION OF MANAGEMENT
Authors: Oleg Kshivets ,
Centre: surgery department, Kaluga Cancer Center

Poster most viewed in this topic
Poster: 14
Visits: 141
Title: A Tumor-penetrating Recombinant Protein anti-EGFR-iRGD Enchance Efficacy of Paclitaxel in 3D multicellular spheroids and Gastric Cancer in vivo
Authors: huizi sha ,
Centre: The Comprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University


 




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