22-24 February, Rotterdam
PO6-11-YI | Caspases compromise SLU7 and UPF1 stabil.. | Carla Rojo .. | María Gárate-Rascón, Miriam Re.. | Basic Science.. | - - |
PO5-11-YI | Imparing proliferation, survival and inv.. | Savino Paradiso .. | .. | Basic Science.. | - - |
PO7-12 | Declining Hepatitis C virus-related Hepa.. | Muhammad Ali Tariq .. | Aeman Asrar.. | Clinical Science.. | - - |
PO8-12 | Atezolizumab-targeted liposomal doxorubi.. | Ilaria Zanotto .. | .. | Basic Science.. | - - |
PO6-12-YI | Dissociation between acute liver decompe.. | Martina Rosi .. | .. | Clinical Science.. | - - |
PO5-12-YI | Role of ganglioside GD2 in the stem-like.. | Mirella Pastore .. | A. MANNINI, M. PASTORE, M. COR.. | Basic Science.. | - - |
PO2-12 | The synergic effect of metformin with at.. | Andrea Dalbeni .. | .. | Clinical Science.. | - - |
PO1-12 | High-dimensional spatial profiling of th.. | Bertram Bengsch .. | .. | Basic Science.. | - - |
PO3-12-YI | Circulating vesicle microRNAs for metabo.. | Santiago Iturbe-Rey .. | A. LAPITZ1,2, L. IZQUIERDO-SAN.. | Basic Science.. | - - |
PO4-12-YI | In silico electrophysiology investigatio.. | Chitaranjan Mahapatra .. | .. | Basic Science.. | - - |
PO3-13-YI | Combined extracellular matrix remodellin.. | Ravi Jagatia .. | .. | Basic Science.. | - - |
PO4-13-YI | The correlation between Interleukin-6 an.. | Mohamed Shafi Mahboob Ali .. | .. | Clinical Science.. | - - |
PO1-13 | Inhibition of the transmembrane transpor.. | Lauriane Blukacz .. | .. | Basic Science.. | - - |
PO2-13-YI | Modeling cancer cells and tumor vasculat.. | Francesco Damone .. | .. | Clinical Science.. | - - |
PO5-13 | Aptamers targeting HuR SUMOylation as a .. | Patricia Peña-San Felix .. | Blanca Baños Jaime, Laura Corr.. | Basic Science.. | - - |
PO7-13-YI | The role of tumor molecular profiling in.. | Giulia Tesini .. | .. | Clinical Science.. | - - |
PO8-13-YI | Biliary tract cancers (BTC): molecular p.. | Valentina Zanuso .. | .. | Clinical Science.. | - - |
PO6-13-YI | The prognostic impact of viral and non-v.. | Federico Rossari .. | .. | Clinical Science.. | - - |
PO8-14-YI | Implications and therapeutic potential o.. | Leidy Estefanía Zapata-Pavas .. | .. | Basic Science.. | - - |
PO5-14-YI | Adverse events (AEs) as potential predic.. | Mara Persano .. | .. | Clinical Science.. | - - |
Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy
Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.
Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.
Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.
Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.