22-24 February, Rotterdam
PO2-1 | A modified Charlson Comorbidity Index to.. | Eleonora Alimenti .. | .. | Clinical Science.. | - - |
PO3-1-YI | Role of Nrf2 signaling in the crosstalk .. | Natalia García-Villasante .. | .. | Basic Science.. | - - |
PO4-1-YI | Targeting endoplasmic reticulum-stress p.. | Jaafar Khaled .. | .. | Basic Science.. | - - |
PO8-1 | Efficacy and safety of atezolizumab-beva.. | Bernardo Stefanini .. | .. | Clinical Science.. | - - |
PO6-1 | Characterization of ENTOSIS, a cell cann.. | Violaine Moreau .. | .. | Basic Science.. | - - |
PO5-1 | Idarubicin-infused transarterial chemoem.. | Jaafar Khaled .. | .. | Clinical Science.. | - - |
PO7-1 | a-FAtE: a new predictive score of respon.. | Federico Rossari .. | .. | Clinical Science.. | - - |
PO4-2 | Cholangiocarcinoma across England: evide.. | Shahid Khan .. | .. | Clinical Science.. | - - |
PO8-2 | Readability, reliability, and accuracy o.. | Justin Tse .. | .. | Clinical Science.. | - - |
PO7-2-YI | Erodosteine attenuates metabolic dysfunc.. | Jatin Sharma .. | .. | Basic Science.. | - - |
PO6-2 | Involvment of the potassium channel ERG1.. | Mirella Pastore .. | J. IORIO, G. ALLA VILIGIARDI, .. | Basic Science.. | - - |
PO5-2 | Emerging role of oncogenic -CATENIN in E.. | Violaine Moreau .. | .. | Basic Science.. | - - |
PO3-2 | Volumetry-based assessment of post-hepat.. | Alexander Gerlach .. | A. MURTHA-LEMEKHOVA, J.FUCHS, .. | Clinical Science.. | - - |
PO2-2 | effect of atorvastatin together with rif.. | Mario Álvares-Da-Silva .. | Ezequiel Ridruejo, Zahira Deza.. | Basic Science.. | - - |
PO1-2-YI | Circulating hypermethylated RASSF1A as a.. | Mohamed Abdel-Samiee .. | .. | Clinical Science.. | - - |
PO1-3-YI | Evaluation of glycemia and diabetes as p.. | Antonio Acquaviva .. | .. | Clinical Science.. | - - |
PO2-3 | Treatment of Hepatocellular Carcinoma ac.. | Lorenzo Canova .. | Massimo Iavarone, Eleonora Ali.. | Clinical Science.. | - - |
PO3-3-YI | MAP17 stimulates mitochondrial activity .. | Claudia Gil-Pitarch .. | .. | Basic Science.. | - - |
PO5-3-YI | Targeting hepatocellular carcinoma: eval.. | Esra Nalbat .. | Ece Akhan Güzelcan, Sumeyye Tu.. | Basic Science.. | - - |
PO6-3 | Lenvatinib (L) versus sorafenib (S) seco.. | Mara Persano .. | .. | Clinical Science.. | - - |
Thunderstorm-related asthma in patients sensitised to olea europaea pollen: twenty emergency department visits for asthmatic symptoms in one single day Losappio, Laura1; Heffler, Enrico2; Falco, Antonio1; Contento, Francesco1; Cannito, Cosimo1; Rolla, Giovanni2 1"Dimiccoli" Hospital, Emergency Department, Barletta, Italy; 2University of Torino - AO Mauriziano "Umberto I", Allergy and Clinical Immunology, Torino, Italy
Background: Associations between thunderstorm and asthma morbidity have been reported in several countries. Common to all epidemics of thunderstorm-related asthma is a significant increase in atmospheric allergen load during and immediately after a thunderstorm. Sensitization to Alternaria species or to grass and parietaria pollens has been suggested to play a key role in thunderstorm-related asthma. The only reported event of thunderstorm-related asthma in Mediterranean area was attributed to sensitization to parietaria pollen.
Method: here we describe a series of 20 patients who presented to Emergency Department in Barletta (94,000 inhabitants), Puglia (Italy) for sudden and severe asthmatic symptoms between May 27th and 28th 2010 (from15:36 to 5:02), immediately after a violent thunderstorm which occurred following a very hot morning (mean temperature: 29°C). All the patients have been subsequently visited by an allergist and underwent allergological work-up which included skin prick tests and a careful clinical history. Local pollen counts were available.
Result: Between May 10th and June 10th 2010, 86 Emergency Department asthma visits were recorded, 20 of them during the study day. Patients' mean age was 44.25 +/- 18.5 years (range: 9-81), 8/20 females, 2 smokers, 16 with a previous history of known respiratory allergy. Only two patients regularly took anti-asthma drugs. All 20 patients were sensitized to Olea europaea pollen, 7 of whom were monosensitized. Ten patients were sensitized to grass, 7 to parietaria, 5 to compositae, 5 to cypress, 5 to house dust mites, 3 to dog and 1 to cat danders. No patient was sensitized to Alternaria. Mean pollen count was 17 granules/m3 for Olea europaea, 6 granules/m3 for grass pollen.
Conclusion: This is, in our knowledge, the second epidemic of thunderstorm related asthma described in Mediterranean area and the first one in which sensitization to Olea europaea played a key-role. In conclusion, our report indicates that thunderstorm asthma may involve different allergens (not only fungal spores and grass or parietaria pollen) in different geographic areas, depending on the seasonality of thunderstorms and allergenic pollen.